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Propelling Your Downstream Purification

AGC Bio and GORE working together

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Reduce your manufacturing footprint
Simplify the process with single-use technology
Lower consumables costs and lead-time
Increase capacity up to 100% and process more material faster

The power of the partnership

GORE®  technology and the power of the AGC Biologics CDMO network combine to offer a new way to advance products into the clinic, offering the benefit of continuous bioprocessing, without the risk. 

Improve your downstream purification through a unique blend of GORE's protein capture devices and AGC Biologics' innovative global scientific network and single-use manufacturing systems. 

GORE's technology for increasing the productivity of the Protein A step seamlessly plugs into AGC's purification steps for your drug substance, giving you innovative purification technology alongside a global manufacturing network offering 30 years of scientific and regulatory expertise.

Separate we are great, but together we are even better. Discover how AGC and GORE can help you meet your next clinical milestone. 


Improving processes and speeding up timelines


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It's simple. Improve your downstream purification productivity of the Protein A step using GORE's technology, and leverage world-class development, analytical and quality control services from AGC Biologics. 

The power of Protein A: The new age of personalized medicine often means smaller batches with higher potency and lower doses. Traditional protein A resin tends to be oversized and underutilized leading to a larger manufacturing footprint, waste, and a more complex process incurring higher costs for clinical bioprocessing and GMP manufacturing.  GORE technology, reduces complexity and risk and has been demonstrated to boost productivity 6-10x over resin, to simplify one of the most expensive and critical steps in your clinical journey.  

Gore’s pre-packed columns use a unique membrane that offers high
dynamic binding capacity at a short residence time. Designed to increase the
efficiency of protein A column purification processes, the Devices accommodate rapid cycle capability at low pressure drop. GORE Protein Capture Device consistently scale from 1mL to 1-L without compromising binding capacity, speed, or elution width (volume).  While demonstrating the ability to withstand multiple cleaning cycles, these Devices can be used as single-use, eliminating the risk associated with storing resin.

The promise of single-use manufacturing technology: AGC Biologics is able to offer increased flexibility and lower clinical and commercial manufacturing costs for customers via a single-use technology platform process. This also comes backed by a strong supply chain and decades of regulatory expertise. 

With both, you can achieve your continuous bioprocessing productivity goals, at the best manufacturing yields possible, while staying within a well-characterized and validated batch process.   

Using GORE and AGC Biologics, you will revel in consistent scale-up performance rivaling resin-based systems without the complexity and expense of new equipment or re-engineering.  

Eliminating Downstream Bottlenecks whitepaper-download-graphic


Setting a new standard in downstream processing

Download this article on how AGC Biologics and GORE are working together to boost productivity in antibody-based therapies.


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About Gore

W. L. Gore & Associates is a global materials science company dedicated to transforming industries and improving lives. Since 1958, Gore has solved complex technical challenges in demanding environments — from outer space to the world’s highest peaks to the inner workings of the human body. With more than 12,000 associates and a strong, team-oriented culture, Gore generates annual revenues of $4.5 billion. For more information, visit gore.com.


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GORE Protein Capture Devices with Protein A

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