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Propelling Your Downstream Purification

AGC Bio and GORE working together

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Reduce your manufacturing footprint
Simplify the process with single-use technology
Lower consumables costs and lead-time
Increase capacity up to 100% and process more material faster

The power of the partnership

GORE®  technology and the power of the AGC Biologics CDMO network combine to offer a new way to advance products into the clinic, offering the benefit of continuous bioprocessing, without the risk. 

Improve your downstream purification through a unique blend of GORE's protein capture devices and AGC Biologics' innovative global scientific network and single-use manufacturing systems. 

GORE's technology for increasing the productivity of the Protein A step seamlessly plugs into AGC's purification steps for your drug substance, giving you innovative purification technology alongside a global manufacturing network offering 30 years of scientific and regulatory expertise.

Using GORE alongside AGC Biologics' CDMO services, you get consistent scale-up performance rivaling resin-based systems without the complexity and expense of new equipment or re-engineering.

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Study: Protein A Membrane vs. Resin Columns

A comparison of this new Protein A capture technology with traditional resin-based approaches. 

Access Research

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Improving processes and speeding up timelines

 

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Got a project? Let's talk

It's simple. Improve your downstream purification productivity of the Protein A step using GORE's technology, and leverage world-class development, analytical and quality control services from AGC Biologics. 

The power of Protein A: The new age of personalized medicine often means smaller batches with higher potency and lower doses. Traditional protein A resin tends to be oversized and underutilized leading to a larger manufacturing footprint, waste, and a more complex process incurring higher costs for clinical bioprocessing and GMP manufacturing.  GORE technology, reduces complexity and risk and has been demonstrated to boost productivity 6-10x over resin, to simplify one of the most expensive and critical steps in your clinical journey.  

The promise of single-use manufacturing technology: AGC Biologics can offer increased flexibility and lower clinical and commercial manufacturing costs for customers via a single-use technology platform. This is backed by a strong supply chain and decades of regulatory expertise. 

With both, you can achieve your continuous bioprocessing productivity goals, at the best manufacturing yields possible, while staying within a well-characterized and validated batch process.    

Eliminating Downstream Bottlenecks whitepaper-download-graphic

Setting a new standard in downstream processing

Download this article on how AGC Biologics and GORE are working together to boost productivity in antibody-based therapies.

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About Gore

W. L. Gore & Associates is a global materials science company dedicated to transforming industries and improving lives. Since 1958, Gore has solved complex technical challenges in demanding environments — from outer space to the world’s highest peaks to the inner workings of the human body. With more than 12,000 associates and a strong, team-oriented culture, Gore generates annual revenues of $4.5 billion. For more information, visit gore.com.

 

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GORE Protein Capture Devices with Protein A

Learn more about AGC Biologics' services and capabilities