Chiba Facilities



With state-of-the-art clinical and commercial manufacturing facilities across the United States, Europe and Asia, AGC Biologics has the capacity and flexibility to meet each customer’s individual manufacturing needs. Our manufacturing facilities are multi-process, engineered for unilateral flow and segregated to produce multiple products at different stages of manufacturing in multiple parts of the facility. This increases the flexibility and number of manufacturing solutions available to meet clients’ rigorous manufacturing and quality needs. Right. On Time.

  • Upstream GMP Suite (Small scale)
  • Upstream GMP Suite (Bioreactors)
  • Quality Control Lab
  • Quality Control Lab
  • GMP Manufacturing lab
  • Downstream Process Development


Contact Us
10, Goikaigan, Ichihara City
Chiba 290-8566 Japan
Tel: +81 3 3218 5694


General Manager

Jun Takami


Our multi-purpose, highly-efficient Chiba microbial and mammalian facilities are compatible with diverse processes, with a core structure and gravity-based facility design that guarantees flexibility and high quality.
The microbial facility offers vast experience with cGMP manufacturing for a large number of projects ranging from E. coli to yeasts.
The mammalian facility guarantees capacity and technological flexibility, including extensive adoption of single-use systems.


cGMP Microbial Manufacturing Line

  • 3,000L Fermenter, Stainless Steel
  • 220L Fermenter, Stainless Steel
  • High Cell Density Fermentation
  • Inclusion Body Recovery
  • Refolding
  • Endotoxin Removal
  • Scale-up & Process Optimization
  • Large Scale Fermentation and Purification
  • Centrifugal Separation
  • Homogenization
  • Membrane Separation
  • Chromatography Purification

cGMP Mammalian Manufacturing Line

  • 2,000L single-use Bioreactor

  • 500L single-use Bioreactor

  • Chromatography and Membrane Purification

  • Fully single-use Technology and Closed Approach


Process Development

  • Upstream Development including 50L single-use Bioreactor for Mammalian Processes
  • Downstream Development
  • Analytical Development