Case Studies & Customer Stories
Robust, Scalable Manufacturing
N-Linked Glycan Analysis for Complex Glycoproteins
The Challenge — The client had an established cell line and process for a complex glycoprotein that produced high-quality material but had a low yield and was not scalable. With plans to move into clinical development, AGC Biologics was challenged to develop a robust, scalable manufacturing process for this molecule while addressing the unique project parameters and production requirements.
Get your antibody produced right. On time.
The Challenge — Accelerating the development and manufacture of monoclonal antibodies is critical for reducing the time it takes to move a promising therapy from bench to clinic. Learn how AGC Biologics can deliver at least 500 grams of monoclonal antibody manufactured under cGMP in just 12 months for €2 million.
Optimizing a Perfusion Manufacturing Process for Commercial Production
The Challenge —Optimize and scale up a bench-scale perfusion manufacturing process for a client developing its first recombinant DNA-based product. The project required the scale-up of a complex process and the development of validated analytics that would support commercial manufacture.
At-Scale LVV Production
Scaling From Cell Factory™ Systems to an iCELLis® 500 Bioreactor without Affecting Critical Quality Attributes
The Challenge —Evolving from the well-established GMP 48L Nunc™ Cell Factory™ (CF) process, identify an effective, replicable, and large-scale lentiviral vector (LVV) manufacturing process to meet the growing manufacturing demand – especially for market application – without affecting critical quality attributes.